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Cancer Right now, cancer is one of the most feared diseases in the world. In


the early 1990s almost 6 million new cancer cases developed and more than 4 million deaths


from cancers occurred. Also more than one-fifth of all deaths were caused by cancer and it


has been predicted, by the American Cancer Society, that about 33% of Americans will


eventually develop this disease. This is a huge disease that is killing people all over


the world.


The field of cancer study is called Oncology. The government has spent


billions of dollars on research of this fatal disease. Cancer is the most aggressive


disease of a larger class known as neoplasms. Neoplasms do not fully comply with the parts


of the cell that control the growth and functions of the cell. These cells eventually


become abnormal growths and can be recognized as not normal tissue. These traits are


passed down as the cell reproduces therefore spreading the cancer.


Neoplasms are generally classified into two groups: malignant and


benign. Malignant tumors, or abnormal tissue, grow more rapidly than benign tissue and


they invade normal tissue. Benign tissue is structured similar to normal tissue while


malignant tissue is abnormal and has an unstructured appearance. Of greater importance,


benign tissue does not metastasize, or begin to grow in other sites, like malignant tumors


do. Cancer always refers to metastasized tumors but the term tumor is not always


necessarily cancer. A tumor is any living tissue that is distinguishable as abnormal


living tissue.


After a cancer forms, it can also change from a benign to a malignant state, therefore


making the cell grow at a more rapid rate. The development of the cell starts when it


forms notable abnormalities in chromosomes and then multiplies exceedingly. Then


metastasis usually occurs and generally causes the death of the host.


There are many different cancers which form on just about all parts of the body. In the


US, skin cancer is the most common cancer, then prostate cancers in males, and then breast


cancer in women. Leukemia is clearly the dominant cancer in children. The number one


killing cancer in the world today is lung cancer, mostly caused by the smoking of


cigarettes. Some researchers have stated that if Americans stopped smoking, lung-cancer


deaths could disintegrate within two decades. Stomach cancer is the second most fatal


cancer in males and Third is the leading cancer in women, breast cancer.


The prevention of cancer rides upon what is known about the causes. Any agent that causes


cancer is called a carcinogen. Carcinogens are generally classified into three groups-


chemical, biological, and physical.


Chemicals that cause cancer have many different molecular structures and can be just about


any type of chemical. Some substances that cause cancer are complex chemicals and gases,


certain metals, drugs, hormones, substances in molds and plants and many more. Many


nitrosamines, or simple organic oxides of nitrogen, are carcinogenic. That and


hydrocarbons are carcinogens in cigarette smoke and increase the risk of lung cancer. Also


another chemical gas, vinyl chloride, gas has been found to be an agent of sarcoma of the


blood vessels in the liver. Many drugs as well as alkylating agents used to treat cancer


are carcinogenic. Even though these chemicals break the DNA of cancerous cells, which


kills them, it also induces cancer in normal cells. Some hormones created in humans can


also cause cancer. High levels of estrogen, which is marked as a female hormone, can


increase the chances of getting a cancer of the uterus (in women). Aflatoxin B is a


substance produced by the mold Aspergillus that causes a number of c


ancer, but generally liver cancer. Many carcinogens have not been discovered but research


is being done to discover other carcinogens to keep people aware and safe.


There are also many different biological agents which cause cancers. The most common


biological agents are the oncogenic viruses that commonly bring about the formation of


neoplasms in some smal

ler animals. Also some of these viruses are thought to cause human


cancers, and one has even been proven to cause leukemia. These viruses can be split into


DNA viruses and RNA viruses, depending on their genetic structure. The DNA viruses


generally insert the genetic information straight into the cells of their host. The RNA


virus, contrasting, requires that the genetic information be transcribed into DNA by an


enzyme, called reverse transcriptase, provided by the virus. All onconogenic viruses have


one or more genes that are needed for the transformation of the infected cell into the


neoplastic cell. These genes, called oncogenes, are best portrayed in the genomes of


oncogenic RNA virus. It is now seen that the oncogenes have close relation with the


counterparts in the normal cells which they infect. The oncogene, non


etheless, has a different structure and appears to be activated and expressed abnormally


by one mechanism or another, leading to transformation in the cell. Some oncogenic viruses


may activate the normal cellular counterparts of oncogenes, called c-oncogenes, thus


causing the neoplastic transformation to occur. Similar reactions may be a result from the


action of chemicals or radiation or both.


Ultraviolet and high-energy radiation are also agents for some types of cancer. A bond


exists between exposure to the sun’s ultraviolet rays and the occurrence of skin


cancer in humans. Some cancers caused by radiation are leukemia, along with cancers of the


thyroid, breast, stomach, uterus, and bone. Consequently everyday diagnostic tools such as


the X ray are used very carefully so that a person is not overexposed. Physically induced


sarcomas can also be induced when films or disks are enclosed under the skin, as done in


experimental animals. After the implant has been in the animal for many years, sarcomas


usually develop around the implant. If the implant is pulverized or its structure is


markedly altered before insertion, no sarcomas develop. This shows that the physical


structure causes the cancer, other than the chemical composition.


Even though it is unknown why cancer happens in some people and not in others heredity


seems to have an effect in some forms of cancer. Because of this, family history may be


significant in predicting and diagnosing cancer.


Prevention is the best way to avoid cancer. Since the majority of cancer is related to the


environment, it would be best to identify and control these factors. There are two tests


to discover carcinogens. The Ames test measures the ability of a substance to cause


mutations in bacteria and is more than 90 percent effective. The alternative is animal


testing. It is exhausting and expensive work but it is the only certain way to be sure if


a particular agent is carcinogenic.


One of the most important ways to protect yourself is early detection. It is stressed that


you get treatment as soon as possible. The American Cancer Society has come up with seven


warning signs of cancer to help you identify cancer symptoms and get help early. They are:


1.a change in bowel or bladder functions; 2.a sore that does not heal; 3.unusual bleeding


or discharge; 4.a thickening or lump on the body; 5.indigestion or trouble swallowing;


6.an obvious change in a wart or mole; and 7. A nagging cough or hoarseness. If one or


more of these symptoms are present a person is advised to see a doctor immediately.


If treatment of a cancer is to be successful, the diagnosis must be as


early as possible. Though no tests have been discovered to detect all cancers, there are


tests to pick up some. A pap test is used to search for cancer of the uterine cervix.


Mammograms are used to detect breast cancer and blood and stool tests are used to find


colon cancer. There are many other tests besides these to test for all different types of


cancer. There are really three different types of cancer. Surgical removal is the first,


it is the most basic treatment. It is used to remove the cancerous legions in the body.


The second is radiation therapy, which uses radiation to try and kill the tumor. One of


the main problems with that is not only does it kill cancerous tissue, it also kills


healthy ones. The third way to treat cancer is chemotherapy, which is treatment by


chemical agents. The chance of complet

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