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The Fine Art Of Making Poison Essay

, Research Paper


Ed Schantz and his apprentice, Eric Johnson, work in a


very strange field of science. They grow and Harvest the


worlds strongest poison. It is, in their words, ?six million


times stronger than rattlesnake venom.? The toxin is


produced by a single-celled bacteria called Botulinum. The


botilin poison produced by the bacteria causes a form of


food poisoning called botulism. Botilin shuts down nerve


pulses from the brain making the victim paralyzed. The


victims usually suffocate to death when their diaphragm


becomes paralyzed. However, Ed and Eric do not use the toxin


for morbid acts of terrorism; they use it to heal people


with muscular disorders.


Electric impulses from the brain cause muscles to


contract. The toxin attaches itself to the nerve endings and


cuts the flow of neurotransmitters, a nerve signal


transmitting chemicals. Some disorders, called dystonias,


send too many and or random impulses. Ed has learned that by


inserting the toxin in very small amounts into the nerves


these extra impulses will be cut off. The nerve endings will


be weakened for a few months until new nerve endings can


grow around the toxins.


In Schantz?s early years of toxin making, he met up


with a doctor named Alan Scott. Scott contacted Ed to see if


he could use botilin to cure Strabismus ,or cross-eye, a


disorder that acts like many dystonias. After testing the


process on monkeys, Ed was given an affirmation in 1978 by


the FDA to proceed with the treatment on humans. Scott also


learned to use the toxin as a cure for blepharospasm; or


excessive and uncontrollable blinking, which previously had

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no cure.


Though the years the toxin?s range of use expanded.


Amazingly every dose of botilin ever given was taken from


the 1979 harvest of the bacteria. The process to make the


bacteria starts in their closet sized lab. They can grow the


bacteria in about three days. The bacteria is then dissolved


in a fluid and sulfuric acid is added. The toxin becomes


insoluble because of the acid and settles out. This process


is repeated in varying methods until the toxin is almost


pure. Finally, ammonium sulfate is added to make the toxin


crystallize into ?glasslike needles? that are pure botilin.


Ed and Eric relate the process to an art. If you are


just a little off in one of the steps, especially


crystallization, then you will not get the result you want,


pure crystals. They also will not use any of the modern or


automated techniques like columns or chemical reactors,


since they do not produce a toxin that is as pure as their


technique. Their technique could be improvised in a home


kitchen but maintaining the high toxicity and desired


properties of the toxin are what takes years of practice to


master.


The 1979 batch of botilin that is being used for


medical treatment is expected to last for another five years


, but researchers that need the toxin to experiment on are


what keeps Ed and Eric in business. The toxin has been found


to help in many diseases including: multiple sclerosis,


cerebral palsy, and stuttering. The toxin is being used in


more and more cases than ever before, and the list is still


growing. Even the Food Research Institute is using the


bacteria to build up an immunity to botulism.

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